Expression of the transformation-sensitive protein "cyclin" in normal human epidermal basal cells and simian virus 40-transformed keratinocytes.
نویسندگان
چکیده
منابع مشابه
Metabolism of a transformation-sensitive amino acid fucoside in normal and simian virus 40-transformed human embryonic lung cells.
We have demonstrated previously that there is a marked decrease in the level of labeled fucose incorporated into an amino acid fucoside, i.e., fucosyl-N-acetylglucosaminylasparagine (FL4c) in SV40-transformed human embryonic lung cells (SV40-WI-38) as compared to WI-38 cells (Morton, P.A., Klinger, M. M., and Steiner, S. Cancer Res., 42: 3022-3027, 1982). In the current study, we have observed ...
متن کاملSimple epithelial nature of some simian virus-40-transformed human epidermal keratinocytes.
Previous studies have indicated that some Simian-virus-40-transformed human epidermal keratinocytes (SV40-HE) undergo significant changes in their growth and differentiated properties. To better understand the significance of these changes, we have characterized the keratins of SV40-HE cells by one- and two-dimensional immunoblot analysis using the subfamily-specific AE1 and AE3 monoclonal anti...
متن کاملMetabolism of a Transformation-sensitive Amino Acid Fucoside in Normal and Simian Virus 40-transformed Human Embryonic Lung Cells1 SheldonM.Steiner2andPhillipA.Morton
We have demonstrated previously that there is a marked decrease in the level of labeled fucose incorporated into an amino acid fucoside, i.e., fucosyl-W-acetylglucosaminylasparagine (FL4c) in SV40-transformed human embryonic lung cells (SV40-WI-38) as compared to WI-38 cells (Morton, P. A., Klinger, M. M., and Steiner, S. Cancer Res., 42: 3022-3027, 1982). In the current study, we have observed...
متن کاملTransformation of human skeletal muscle cells by simian virus 40.
Molecular studies of the biochemical alterations involved in human myopathies have been restricted because of the finite life-span and slow growth rate of cultures derived from primary tissue. Because the tumor virus simian virus 40 (SV40) can alter both the growth properties and longevity of human cells, we have infected skeletal muscle cultures derived from four biopsies with a small-plaque v...
متن کاملSuperinfection of simian virus 40-transformed permissive cells with simian virus 40.
Evidence that the resistance of simian virus (SV40)-transformed permissive cells to superinfection with SV40 is due to lack of virus uptake is presented. When virus uptake is enhanced, the events of infection proceed as in normal permissive cells, resulting in production of infectious virus.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1984
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.81.10.3128